Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

Hyung-Gu Kim, Li Tan, Ellen Weisberg, +13

ACS Chemical Biology

Drug TargetMolecular BiologyCytoskeletonPharmacotherapySignaling Pathway +18

Determining Cysteines Available for Covalent Inhibition Across the Human Kinome

Zheng Zhao, Qingsong Liu, Spencer Bliven, +2

Journal of Medicinal Chemistry

Cysteine ReactivityCysteine Thiol GroupMolecular BiologyCytoskeletonChemical Biology +15

Brain Penetrant LRRK2 Inhibitor

Hwan Geun Choi, Jinwei Zhang, Xianming Deng, +5

ACS Medicinal Chemistry Letters

Wild-type Lrrk2PharmacotherapySynaptic SignalingSocial SciencesMolecular Pharmacology +16

Performance of a full-scale modified anaerobic/anoxic/oxic process: High-throughput sequence analysis of its microbial structures and their community functions

Yasong Chen, Zheng Zhao, Yuke Peng, +3

Bioresource Technology

EngineeringBioenergeticsBioremediationMicrobial Electrochemical SystemCommunity Functions +9

Kinome-wide Selectivity Profiling of ATP-competitive Mammalian Target of Rapamycin (mTOR) Inhibitors and Characterization of Their Binding Kinetics

Qingsong Liu, Sivapriya Kirubakaran, Wooyoung Hur, +18

Journal of Biological Chemistry

Drug TargetAtp-competitive Mammalian TargetMolecular BiologyAtp-competitive Mtor InhibitorsChemical Biology +26

An improved Carius tube technique for determination of low concentrations of Re and Os in pyrites

Liang Qi, Mei‐Fu Zhou, Jianfeng Gao, +1

Journal of Analytical Atomic Spectrometry

EngineeringTrace Element GeochemistryHydrothermal PyritesChemistryMineral Processing +14

Crystal Structure of the GRAS Domain of SCARECROW-LIKE7 in<i>Oryza sativa</i>

Shengping Li, Yanhe Zhao, Zheng Zhao, +4

The Plant Cell

Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitors

Ellen Weisberg, Qingsong Liu, Erik A. Nelson, +14

Leukemia

Mutant Flt3-positive AmlOncologyMedicineCombination TherapyPharmacotherapy +7

Atomic Fe Embedded in Carbon Nanoshells–Graphene Nanomeshes with Enhanced Oxygen Reduction Reaction Performance

Congwei Wang, Huinian Zhang, Junying Wang, +6

Chemistry of Materials

Materials ScienceGraphene NanomeshesOxygen Reduction ReactionEngineeringCarbon-based Material +12

A pH responsive tannic acid/quaternized carboxymethyl chitosan/oxidized sodium alginate hydrogels for accelerated diabetic wound healing and real-time monitoring

Zhifei Yang, Chen Wang, Zhiyuan Zhang, +5

International Journal of Biological Macromolecules

Tissue EngineeringHydrogelsReal-time MonitoringBiopolymer GelEngineering +7