Wooyoung Hur

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12

Patient-derived models of acquired resistance can identify effective drug combinations for cancer

Adam Crystal, Alice T. Shaw, Lecia V. Sequist et al. · Science · 2014 · 727 citations · Full text

Allosteric inhibitors of Bcr-abl–dependent cell proliferation

Francisco Adrián, Qiang Ding, Taebo Sim et al. · Nature Chemical Biology · 2006 · 376 citations · Full text

Molecular Pharmacology, Medicine, Allosteric Inhibitors +5

Synthetic small molecules that control stem cell fate

Sheng Ding, Tom Wu, Achim Brinker et al. · Proceedings of the National Academy of Sciences · 2003 · 367 citations · Full text

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1<i>H</i>)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

Qingsong Liu, Jae Won Chang, Jinhua Wang et al. · Journal of Medicinal Chemistry · 2010 · 251 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20