Stéphane De Cesco

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Hai Fang, Hans Wolf, Bogdan Knezevic et al. · Nature Genetics · 2019 · 232 citations · Full text

Life Sciences, Genetics, Immunology +11

Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry

Justin M. Di Trani, Stéphane De Cesco, Rebecca O’Leary et al. · Nature Communications · 2018 · 69 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Virtual Screening and Computational Optimization for the Discovery of Covalent Prolyl Oligopeptidase Inhibitors with Activity in Human Cells

Stéphane De Cesco, Sébastien Deslandes, Éric Therrien et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

3-Oxo-hexahydro-1<i>H</i>-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors

Gaëlle Mariaule, Stéphane De Cesco, Francesco Airaghi et al. · Journal of Medicinal Chemistry · 2015 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

TargetDB: A target information aggregation tool and tractability predictor

Stéphane De Cesco, John B. Davis, Paul E. Brennan · PLoS ONE · 2020 · 24 citations · Full text

Medicine, Bioinformatics, Biomedical Informatics +17