Stéphane De Cesco

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Hai Fang, Hans Wolf, Bogdan Knezevic et al. · Nature Genetics · 2019 · 221 citations · Full text

Drug Target Landscape, Immunogenetics, Genetics-led Approach +12

Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry

Justin M. Di Trani, Stéphane De Cesco, Rebecca O’Leary et al. · Nature Communications · 2018 · 67 citations · Full text

Virtual Screening and Computational Optimization for the Discovery of Covalent Prolyl Oligopeptidase Inhibitors with Activity in Human Cells

Stéphane De Cesco, Sébastien Deslandes, Éric Therrien et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Covalent Inhibitors, Drug Target, Peptide Science +19

3-Oxo-hexahydro-1<i>H</i>-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors

Gaëlle Mariaule, Stéphane De Cesco, Francesco Airaghi et al. · Journal of Medicinal Chemistry · 2015 · 25 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Conformationally Constrained Covalent +14

TargetDB: A target information aggregation tool and tractability predictor

Stéphane De Cesco, John B. Davis, Paul E. Brennan · PLoS ONE · 2020 · 23 citations · Full text

Drug Target, Engineering, Hit Identification +26