Francesco Airaghi

3-Oxo-hexahydro-1<i>H</i>-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors

Gaëlle Mariaule, Stéphane De Cesco, Francesco Airaghi et al. · Journal of Medicinal Chemistry · 2015 · 25 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Conformationally Constrained Covalent +14

The diketopiperazine-fused tetrahydro-β-carboline scaffold as a model peptidomimetic with an unusual α-turn secondary structure

Francesco Airaghi, Andrea Fiorati, Giordano Lesma et al. · Beilstein Journal of Organic Chemistry · 2013 · 15 citations · Full text

Bioorganic Chemistry, Peptide Engineering, Molecular Biology +21

Structural and Biological Exploration of Phe³–Phe⁴-Modified Endomorphin-2 Peptidomimetics

Giordano Lesma, Severo Salvadori, Francesco Airaghi et al. · ACS Medicinal Chemistry Letters · 2013 · 12 citations · Full text

Drug Target, Engineering, Peptide Science +17

Synthesis, pharmacological evaluation and conformational investigation of endomorphin-2 hybrid analogues

Giordano Lesma, Severo Salvadori, Francesco Airaghi et al. · Molecular Diversity · 2012 · 11 citations

Molecular Pharmacology, Conformational Investigation, Biochemistry +6