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Mitomycins and Porfiromycin: Chemical Mechanism of Activation and Cross-linking of DNA

V. N. Iyer, Waclaw Szybalski · Science · 1964 · 567 citations

Bioorganic Chemistry, Engineering, Molecular Biology +18

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

N R Bachur, S Gordon, Malcolm V. Gee et al. · Proceedings of the National Academy of Sciences · 1979 · 492 citations · Full text

P-450 Reductase Activation, Redox Biology, Oxidative Stress +17

Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver.

Hans J. Prochaska, Paul Talalay · PubMed · 1988 · 408 citations

Aldo-keto Reductase, Pathology, Phase Ii Enzymes +22

One-electron-transfer reactions in biochemical systems V. Difference in the mechanism of quinone reduction by the NADH dehydrogenase and the NAD(P)H dehydrogenase (DT-diaphorase)

Takashi Iyanagi, Isao Yamazaki · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1970 · 340 citations

Quinone Reduction, Aldo-keto Reductase, Aldehyde Dehydrogenase +9

[30] DT-diaphorase: Purification, properties, and function

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Enzymatic Modification, Biomolecular Engineering