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Mechanism-based population pharmacokinetic and pharmacodynamic modeling of intravenous and intranasal dexmedetomidine in healthy subjects

Molecular PharmacologyPharmacokinetic ModelingPharmacodynamicsHealthy SubjectsPharmacological StudyPharmacologyIntranasal DexmedetomidineMechanism-based Population PharmacokineticPharmacotherapyMedicinePhysiologically-based Pharmacokinetic ModelingPharmacokineticsPharmacodynamic Modeling