Metabolism of arachidonic acid in rabbit ocular tissues.

Abstract

C- PGEarachidonic acid in both tissues at the expense of the other reaction products. In the presence ofboth co-factors (epinephrine and GSH), the reaction products were similar to that of epineph-rine alone. No reaction products were obtained when boiled or indomethacin-treated (5.6 /JM)tissue samples were incubated with arachidonic acid under the same conditions. Pre-incubationof tissue samples with imidazole (1.4 mM) prevented the