Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit et al. · International Journal of Cancer · 2014 · 29K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

Life Sciences, Genetics, Molecular Biology +16

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

Life Sciences, Developmental Biology, Genetics +14

MeCP2 Is a Transcriptional Repressor with Abundant Binding Sites in Genomic Chromatin

Xinsheng Nan, Francisco J. Campoy, Adrian Bird · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2

Juan I. Young, Eugene P. Hong, John C. Castle et al. · Proceedings of the National Academy of Sciences · 2005 · 484 citations · Full text

Medicine, Genetics, Molecular Genetics +17