Concepedia

A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNA

Alan Diot, Alex Hinks-Roberts, Tiffany Lodge, Chunyan Liao, Eszter Dombi, Karl Morten, Stefen Brady, Carl Fratter, Janet Carver, Rebecca Muir,

Pharmacological Research · 2015 · 53 citations · 29 references

DOI

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29

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe et al. · Autophagy · 2016 · 6K citations · Full text

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Methods in Mammalian Autophagy Research

Noboru Mizushima, Tamotsu Yoshimori, Beth Levine · Cell · 2010 · 4.5K citations · Full text

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich et al. · Autophagy · 2012 · 4K citations · Full text

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

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