Concepedia

Culture temperature modulates monoclonal antibody charge variation distribution in Chinese hamster ovary cell cultures

Xintao Zhang, Yating Sun, Hongping Tang, Fan Li, Dongdong Hu, Jintao Liu, Xuping Liu, Wen‐Song Tan

Biotechnology Letters · 2015 · 24 citations · 18 references

DOI

Concepts

References

18

Identification of multiple sources of charge heterogeneity in a recombinant antibody

Reed J. Harris, Bruce Kabakoff, Frank Macchi et al. · Journal of Chromatography B Biomedical Sciences and Applications · 2001 · 503 citations

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Charge variants in IgG1

Leslie A. Khawli, Sirj Goswami, Ryan Hutchinson et al. · mAbs · 2010 · 417 citations · Full text

, , +17

What's fueling the biotech engine—2012 to 2013

S. Aggarwal · Nature Biotechnology · 2014 · 255 citations

, , +1

Effect of low culture temperature on specific productivity, transcription level, and heterogeneity of erythropoietin in Chinese hamster ovary cells

Sung Kwan Yoon, Ji Yong Song, Gyun Min Lee · Biotechnology and Bioengineering · 2003 · 244 citations · Full text

, , +15

Asparagine Deamidation Dependence on Buffer Type, pH, and Temperature

Amanda L. Pace, Rita Wong, Yonghua Taylor Zhang et al. · Journal of Pharmaceutical Sciences · 2013 · 153 citations

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