Leslie A. Khawli

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8

Charge variants in IgG1

Leslie A. Khawli, Sirj Goswami, Ryan Hutchinson et al. · mAbs · 2010 · 406 citations · Full text

Immunocytochemical Technique, Immunology, Antibody Charge Variants +18

Impact of Drug Conjugation on Pharmacokinetics and Tissue Distribution of Anti-STEAP1 Antibody–Drug Conjugates in Rats

C. Andrew Boswell, Eduardo E. Mundo, Crystal Zhang et al. · Bioconjugate Chemistry · 2011 · 200 citations

Nanotherapeutics, Local Pharmacology, Immunology +23

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration

Yanan Zheng, Devin B. Tesar, Lisa J. Benincosa et al. · mAbs · 2012 · 135 citations · Full text

Immunocytochemical Technique, Immunology, Pharmacotherapy +17

A novel in vitro method to model the fate of subcutaneously administered biopharmaceuticals and associated formulation components

Hanne Kinnunen, Vikas Sharma, L. Rodrigo Contreras-Rojas et al. · Journal of Controlled Release · 2015 · 110 citations · Full text

Formulation Components, Translational Medicine, Medicine +6