Suppression of tumor growth in lung cancer xenograft model mice by poly(sorbitol-co-PEI)-mediated delivery of osteopontin siRNA

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Pathology, Cancer Biology, Cancer Chemotherapy +17

Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship

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A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity

Dagmar Fischer, Thorsten Bieber, Youxin Li et al. · Pharmaceutical Research · 1999 · 1.2K citations

Evidence for the role of proteoglycans in cation-mediated gene transfer.

Kimberly Ann Mislick, John D. Baldeschwieler · Proceedings of the National Academy of Sciences · 1996 · 764 citations · Full text

Signal Transduction, Gene Complexes, Glycosylation +13

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

Beata Urban-Klein, Stephanie Werth, Shaker Abuharbeid et al. · Gene Therapy · 2004 · 701 citations

Engineering, Systemic Application, Rna Biology +9