Cellular Signalling · 2015 · 22 citations · 45 references
Life SciencesMolecular BiologyPharmacologyEnzymologyMolecular PharmacologySignal TransductionAmino Acid MetabolismEnzyme InhibitionProtein SynthesisMtor Complex 1 RegulationMtor Complex 1 SignalingMtor Signaling
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Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
Ken Inoki, Yong Li, Tian Xu et al. · Genes & Development · 2003 · 1.9K citations · Full text