CYP2D6*10 alleles do not determine plasma fluvoxamine concentration/dose ratio in Japanese subjects

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed · 1997 · 979 citations

Medicine, Genetics, Pharmacology +17

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

Markus H. Heim, Urs Meyer · The Lancet · 1990 · 451 citations

Life Sciences, Genetics, Molecular Genetics +7

Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.

Inger Johansson, Mikael Oscarson, Qun‐Ying Yue et al. · Molecular Pharmacology · 1994 · 430 citations

Medicine, Genetics, Molecular Genetics +16

Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

Vidar M. Steen, Ole A. Andreassen, Ann K. Daly et al. · Pharmacogenetics · 1995 · 243 citations

Medicine, Genetics, Pharmacology +16

Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity*

Juan Antonio Carrillo, Marja-Liisa Dahl, Jan‐Olof Svensson et al. · Clinical Pharmacology & Therapeutics · 1996 · 120 citations

Medicine, Pharmacokinetics, Pharmacology +14