Concepedia

Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches

Osman A. S. B. M. Gani, Balmukund S. Thakkar, Dilip Narayanan, Kazi Asraful Alam, Peter Kyomuhendo, Ulli Rothweiler, Veronica Tello-Franco, Richard A. Engh

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2015 · 15 citations · 70 references

Concepts

BioinformaticsCheminformatics ApproachesMedicineNatural SciencesGene RecognitionComputational BiologyMolecular BiologyProtein Structure PredictionPathway AnalysisSequence AlignmentComparing SequenceSystems BiologyProteomicsFunctional GenomicsProtein BioinformaticsStructural Biology

References

70

Leo Breiman · Machine Learning · 2001 · 119.3K citations · Full text

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 38.9K citations

Biological Database, Biochemistry, Structural Bioinformatics +12

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Stewart T. Cole, Roland Brosch, Julian Parkhill et al. · Nature · 1998 · 7.8K citations · Full text

Pulmonary Tuberculosis, Complete Genome Sequence, Mycobacterium Tuberculosis +10

Random Forest: A Classification and Regression Tool for Compound Classification and QSAR Modeling

Vladimir Svetnik, Andy Liaw, Christopher Tong et al. · Journal of Chemical Information and Computer Sciences · 2003 · 3.5K citations

Engineering, Machine Learning, Hit Identification +24

Comprehensive analysis of kinase inhibitor selectivity

Mindy I. Davis, Jeremy P. Hunt, Sanna Herrgård et al. · Nature Biotechnology · 2011 · 2.3K citations · Full text

Drug Target, Signal Transduction, Medicine +5