Anti-C1q autoantibodies from systemic lupus erythematosus patients activate the complement system via both the classical and lectin pathways

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

Diagnosis, Pathology, Dermatology +19

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

Marina Botto, Chiara Dell' Agnola, Anne E. Bygrave et al. · Nature Genetics · 1998 · 1.4K citations

Glomerular Disease, Glomerulonephritis, Autoimmune Disease +14

C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

Carol Anne Ogden, Aimee M. deCathelineau, Peter Hoffmann et al. · The Journal of Experimental Medicine · 2001 · 1.1K citations · Full text

A Hierarchical Role for Classical Pathway Complement Proteins in the Clearance of Apoptotic Cells in Vivo

Philip R. Taylor, Anna Carugati, Valerie A. Fadok et al. · The Journal of Experimental Medicine · 2000 · 733 citations · Full text

Apoptosis, Immunology, Cell Death +25

Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity

Peter E. Lipsky · Nature Immunology · 2001 · 700 citations

Autoimmune Disease, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus Treatment +10