Concepedia

Decreased heat stability and increased chaperone requirement of modified human betaB1-crystallins.

Kirsten J. Lampi, Yung H Kim, Hans Peter Bächinger, Bruce A. Boswell, Robyn A. Lindner, John A. Carver, Thomas R. Shearer, Larry L. David, Deborah M. Kapfer

PubMed · 2002 · 54 citations · 63 references

Abstract

Deamidation and truncation of betaB1 led to destabilization of the protein and decreased stability to heat. Decreased stability of lens crystallins may contribute to their insolubilization and cataract formation.

References

63

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

Edgar Schreiber, Patrick Matthias, Michael M. Müller et al. · Nucleic Acids Research · 1989 · 4.2K citations · Full text

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Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations · Full text

, , +13

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

Marc Montminy, Louise M. Bilezikjian · Nature · 1987 · 1.4K citations

, , +9

Cyclic AMP and the induction of eukaryotic gene transcription.

William J. Roesler, G R Vandenbark, Richard W. Hanson · Journal of Biological Chemistry · 1988 · 1K citations · Full text

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