Concepedia

Crystallin Modification

Crystallin Modification is a molecular alteration process that post-translationally modifies crystallin proteins in the ocular lens, distinguishing itself from other protein modifications by its specific role in maintaining lens transparency and contributing to age-related and pathological cataract formation.

535

Publications

26.1K

Citations

1.4K

Authors

381

Institutions

Publications per year

2017–2026

40

Parents

Publications

535

Diabetic cataract formation: potential role of glycosylation of lens crystallins.

Victor J. Stevens, Carol A. Rouzer, Vincent M. Monnier et al. · Proceedings of the National Academy of Sciences · 1978 · 414 citations · Full text

, , +14

Age-Related Changes in Human Crystallins Determined from Comparative Analysis of Post-translational Modifications in Young and Aged Lens:  Does Deamidation Contribute to Crystallin Insolubility?

Phillip A. Wilmarth, Stephen Tanner, Surendra Dasari et al. · Journal of Proteome Research · 2006 · 289 citations · Full text

, , +13

Age-related Changes in Human Lens Crystallins Identified by Two-dimensional Electrophoresis and Mass Spectrometry

Kirsten J. Lampi, ZHIXIANG MA, Stacy R.A. Hanson et al. · Experimental Eye Research · 1998 · 280 citations

, , +14

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.

Ram H. Nagaraj, David R. Sell, Malladi Prabhakaram et al. · Proceedings of the National Academy of Sciences · 1991 · 255 citations

, , +13

Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging.

Nobukazu Araki, N Ueno, Buddhapriya Chakrabarti et al. · Journal of Biological Chemistry · 1992 · 250 citations · Full text

, , +13

1–5 of 535

Authors

1.4K

  1. JB
    Jean B. Smith

    University of Nebraska–Lincoln, United States

    26 publications · 2K citations

    24

    h-index

  2. DL
    David L. Smith

    University of Nebraska–Lincoln, United States

    20 publications · 1.8K citations

    19

    h-index

  3. LT
    L. Takemoto

    Kansas State University, United States

    23 publications · 852 citations

    18

    h-index

  4. RJ
    Roger J.W. Truscott

    University of Wollongong, Australia

    19 publications · 1K citations

    17

    h-index

  5. HB
    H. Bloemendal

    Radboud University Nijmegen, Netherlands

    17 publications · 845 citations

    16

    h-index

1–5 of 1.4K

Institutions

381

  1. Oregon Health & Science University

    Portland, United States

    23 h-index

    89 publications

    8.1K citations

  2. Case Western Reserve University

    Cleveland, United States

    22 h-index

    109 publications

    6.2K citations

  3. National Eye Institute

    Bethesda, United States

    22 h-index

    65 publications

    3.6K citations

  4. University of Wollongong

    Wollongong, Australia

    19 h-index

    48 publications

    2.9K citations

  5. Kansas State University

    Manhattan, United States

    19 h-index

    44 publications

    1.6K citations

  6. Columbia University

    New York, United States

    19 h-index

    55 publications

    2.8K citations

  7. Radboud University Nijmegen

    Nijmegen, The Netherlands

    19 h-index

    77 publications

    4K citations

  8. University of Nebraska–Lincoln

    Lincoln, United States

    19 h-index

    66 publications

    5.7K citations

1–8 of 381

Venues

  1. Experimental Eye Research

    58 publications · 3K citations

    34

    h-index

  2. Journal of Biological Chemistry

    JBC · 50 publications · 4.1K citations

    34

    h-index

  3. PubMed

    Repository · 53 publications · 2.8K citations

    30

    h-index

  4. Biochemistry

    32 publications · 1.9K citations

    28

    h-index

  5. Current Eye Research

    37 publications · 1.1K citations

    22

    h-index

1–5