Antiretroviral Effects of Deoxyhypusyl Hydroxylase Inhibitors

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

Michael H. Malim, Joachim Hauber, Shu‐Yun Le et al. · Nature · 1989 · 1.3K citations

Life Sciences, Molecular Biology, Molecular Genetics +17

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

Terri H. Finkel, Gareth Tudor‐Williams, Nirmal K. Banda et al. · Nature Medicine · 1995 · 948 citations

Life Sciences, Cell Biology, Immunology +15

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Julian He, S Choe, Robert Walker et al. · Journal of Virology · 1995 · 918 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

Michael H. Malim, S Böhnlein, Joachim Hauber et al. · Cell · 1989 · 734 citations

Life Sciences, Biochemistry, Molecular Biology +14

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

T M Folks, Kathleen A. Clouse, J. Shawn Justement et al. · Proceedings of the National Academy of Sciences · 1989 · 718 citations · Full text

Life Sciences, Immunology, Infectious Diseases +12