Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

Françoise Barré‐Sinoussi, Jean‐Claude Chermann, FA Rey et al. · Science · 1983 · 6.9K citations

Life Sciences, Microbiology, Molecular Biology +16

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

Robert C. Gallo, Syed Zaki Salahuddin, Mikuláš Popovič et al. · Science · 1984 · 3.6K citations

Life Sciences, Infectious Diseases, Microbiology +9

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

Andreas Bachmair, Daniel Finley, Alexander Varshavsky · Science · 1986 · 2K citations

Life Sciences, Biochemistry, Molecular Biology +14

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

Michael H. Malim, Joachim Hauber, Shu‐Yun Le et al. · Nature · 1989 · 1.3K citations

Life Sciences, Molecular Biology, Molecular Genetics +17

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

Ian A. Hope, Kevin Struhl · Cell · 1986 · 924 citations

Life Sciences, Genetics, Molecular Biology +13