Use of Mouse Models to Study Plasminogen Activator Inhibitor-1

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

Yutaka Nakashima, Andrew Plump, Elaine W. Raines et al. · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1994 · 1.7K citations

Veterinary Medicine, Cardiology, Pathobiology +17

Increased Plasma Levels of a Rapid Inhibitor of Tissue Plasminogen Activator in Young Survivors of Myocardial Infarction

Anders Hamsten, Björn Wiman, Ulf dé Fairé et al. · New England Journal of Medicine · 1985 · 1.4K citations

Medicine, Cardiology, Clinical Cardiology +10

Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study

T MEADE · The Lancet · 1993 · 714 citations

Medicine, Cardiology, Internal Medicine +12

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization

Khalid Bajou, Agnès Noël, Robert D. Gerard et al. · Nature Medicine · 1998 · 684 citations · Full text

Medicine, Cancer Biology, Oncology +14

Production of Plasminogen Activator Inhibitor 1 by Human Adipose Tissue: Possible Link Between Visceral Fat Accumulation and Vascular Disease

Marie‐Christine Alessi, Franck Peiretti, Pierre‐Emmanuel Morange et al. · Diabetes · 1997 · 604 citations

Life Sciences, Biochemistry, Physiology +16