Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases

Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine.

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Medicine, Pharmacokinetics, Pharmacology +17

Metabolism of nicotine by human liver microsomes: stereoselective formation of trans-nicotine N'-oxide

John R. Cashman, Sang B. Park, Ziping Yang et al. · Chemical Research in Toxicology · 1992 · 213 citations

Medicine, Biochemistry, Pharmacology +17

Renal Effects of Ibuprofen, Piroxicam, and Sulindac in Patients with Asymptomatic Renal Failure

Andrew Whelton · Annals of Internal Medicine · 1990 · 204 citations

Pharmacy, Pharmacology, Pharmacotherapy +14

The molecular biology of the flavin-containing monooxygenases of man

Ian Phillips, Colin T. Dolphin, Philippe Clair et al. · Chemico-Biological Interactions · 1995 · 151 citations

Life Sciences, Biochemistry, Molecular Biology +13

Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans

Lila H. Overby, Geraldine C. Carver, Richard M. Philpot · Chemico-Biological Interactions · 1997 · 145 citations · Full text

Medicine, Biochemistry, Pharmacology +13