Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway

FGF-21 as a novel metabolic regulator

Alexei Kharitonenkov, Tatiyana L. Shiyanova, Anja Köester et al. · Journal of Clinical Investigation · 2005 · 2.1K citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

Jing Xu, David J. Lloyd, Clarence Hale et al. · Diabetes · 2008 · 1.1K citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway

Haruhiko Kouhara, Yaron R. Hadari, Taly R. Spivak-Kroizman et al. · Cell · 1997 · 871 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Tissue-specific Expression of βKlotho and Fibroblast Growth Factor (FGF) Receptor Isoforms Determines Metabolic Activity of FGF19 and FGF21

Hiroshi Kurosu, Mihwa Choi, Yasushi Ogawa et al. · Journal of Biological Chemistry · 2007 · 734 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Matthew J. Potthoff, Takeshi Inagaki, Santhosh Satapati et al. · Proceedings of the National Academy of Sciences · 2009 · 694 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17