Expanded bed adsorption in the purification of monoclonal antibodies: a comparison of process alternatives

Single–Step Recovery of a Secreted Recombinant Protein by Expanded Bed Adsorption

Marianne Hansson, Stefan Ståhl, Rolf Hjorth et al. · Bio/Technology · 1994 · 139 citations

Engineering, Bioengineering, Biotechnology +13

Pilot scale recovery of recombinant annexin V from unclarified <i>escherichia coli</i> homogenate using expanded bed adsorption

Ann‐Kristin Barnfield Frej, Rolf Hjorth, Åke Hammarström · Biotechnology and Bioengineering · 1994 · 135 citations

Engineering, Biotechnology, Microbiology +15

Isolation of monoclonal antibodies from cell containing hybridoma broth using a protein A coated adsorbent in expanded beds

Jörg Thömmes, Andrea Bader, Markus Halfar et al. · Journal of Chromatography A · 1996 · 122 citations

Pharmacy, Biochemistry, Biotechnology +13

Purification of monoclonal antibodies from whole hybridoma fermentation broth by fluidized bed adsorption

Jörg Thömmes, Markus Halfar, Suzanne Lenz et al. · Biotechnology and Bioengineering · 1995 · 96 citations

Pharmacy, Biochemistry, Biotechnology +16

Expanded bed protein A affinity chromatography of a recombinant humanized monoclonal antibody: process development, operation, and comparison with a packed bed method

Robert Fahrner, Gregory S. Blank, Gerardo Zapata · Journal of Biotechnology · 1999 · 50 citations

Life Sciences, Biochemistry, Biotechnology +17