Isolation of monoclonal antibodies from cell containing hybridoma broth using a protein A coated adsorbent in expanded beds

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

Chemical Reaction Engineering

Octave Levenspiel · Industrial & Engineering Chemistry Research · 1999 · 10K citations

Engineering, Chemical Engineering, Chemistry +6

Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization

Shihong Li, Christian Schöneich, Ronald T. Borchardt · Biotechnology and Bioengineering · 1995 · 297 citations

Life Sciences, Biochemistry, Mechanisms Of Toxicity +15

Development of operating conditions for protein purification using expanded bed techniques: The effect of the degree of bed expansion on adsorption performance

Yu-Kaung Chang, Howard A. Chase · Biotechnology and Bioengineering · 2000 · 158 citations

Engineering, Biotechnology, Chemical Engineering +17

Single–Step Recovery of a Secreted Recombinant Protein by Expanded Bed Adsorption

Marianne Hansson, Stefan Ståhl, Rolf Hjorth et al. · Bio/Technology · 1994 · 139 citations

Engineering, Bioengineering, Biotechnology +13