Rewriting regulatory DNA to dissect and reprogram gene expression

Model-based Analysis of ChIP-Seq (MACS)

Yong Zhang, Tao Liu, Clifford A. Meyer et al. · Genome biology · 2008 · 19.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +11

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

Sven Heinz, Christopher Benner, Nathanael J. Spann et al. · Molecular Cell · 2010 · 14.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

Nuala A. O’Leary, Matt W. Wright, J. Rodney Brister et al. · Nucleic Acids Research · 2015 · 7.1K citations · Full text

Life Sciences, Bioinformatics, Biology +17

The MEME Suite

Timothy L. Bailey, James Johnson, Charles E. Grant et al. · Nucleic Acids Research · 2015 · 5.5K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +15

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +10