Gabriella E. Martyn

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Takeshi Masuda, Xin Wang, Manami Maeda et al. · Science · 2016 · 378 citations

Medicine, Genetics, Hematology +12

Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding

Gabriella E. Martyn, Beeke Wienert, Manan Shah et al. · Nature Genetics · 2018 · 297 citations

Life Sciences, Genetics, Molecular Genetics +6

KLF1 drives the expression of fetal hemoglobin in British HPFH

Beeke Wienert, Gabriella E. Martyn, Ryo Kurita et al. · Blood · 2017 · 88 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site

Gabriella E. Martyn, Beeke Wienert, Ryo Kurita et al. · Blood · 2019 · 72 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression

Sarah K. Topfer, Ruopeng Feng, Peng Huang et al. · Blood · 2022 · 59 citations · Full text

Life Sciences, Genetics, Molecular Biology +16