Gabriella E. Martyn

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin

Takeshi Masuda, Xin Wang, Manami Maeda et al. · Science · 2016 · 362 citations

Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding

Gabriella E. Martyn, Beeke Wienert, Lu Yang et al. · Nature Genetics · 2018 · 289 citations

Developmental Biology, Zbtb7a Binding, Genetic Disorder +9

KLF1 drives the expression of fetal hemoglobin in British HPFH

Beeke Wienert, Gabriella E. Martyn, Ryo Kurita et al. · Blood · 2017 · 86 citations · Full text

A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site

Gabriella E. Martyn, Beeke Wienert, Ryo Kurita et al. · Blood · 2019 · 70 citations · Full text

Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression

Sarah K. Topfer, Ruopeng Feng, Peng Huang et al. · Blood · 2022 · 58 citations · Full text