Tetrahydrocurcumin alleviates colorectal tumorigenesis by modulating the SPP1/CD44 axis and preventing M2 tumor-associated macrophage polarization

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Mathieu Laversanne, Hyuna Sung et al. · CA A Cancer Journal for Clinicians · 2024 · 23.1K citations · Full text

Medicine, Oncology, Cancer Control +16

Biotransformation of Curcumin Through Reduction and Glucuronidation in Mice

Min‐Hsiung Pan, Tsang‐Miao Huang, Jen‐Kun Lin · Drug Metabolism and Disposition · 1999 · 943 citations

Pharmacy, Pharmacokinetics, Pharmacology +8

Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer

Jingjing Qi, Hongxiang Sun, Yao Zhang et al. · Nature Communications · 2022 · 931 citations · Full text

Medicine, Immunology, Oncology +17

Immune phenotypic linkage between colorectal cancer and liver metastasis

Yedan Liu, Qiming Zhang, Baocai Xing et al. · Cancer Cell · 2022 · 469 citations · Full text

Life Sciences, Immunology, Oncology +16

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Ying Zhu, Jing Yang, Da Xu et al. · Gut · 2019 · 411 citations

Medicine, Immunology, Oncology +17