Single-cell and spatial analysis reveal interaction of FAP+ fibroblasts and SPP1+ macrophages in colorectal cancer

Jingjing Qi, Hongxiang Sun, Yao Zhang, +18

Nature Communications

Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity

Chao Yang, Jingsi Jin, Yuanqin Yang, +12

Immunity

MedicineT-regulatory CellImmunologySex DifferencesTumor Immunity +7

MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche

Ningbo Wu, Hongxiang Sun, Xiaoyun Zhao, +22

Nature

Cell LineageDevelopmental BiologyMedicineAdult Stem CellStem Cell Research +5

Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1

Rong Tan, Satoshi Nakajima, Qun Wang, +11

Molecular Cell

Genome InstabilityOxidative Dna DamageCell RegulationMolecular BiologyCellular Senescence +3

The intestinal microbial metabolite desaminotyrosine is an anti‐inflammatory molecule that modulates local and systemic immune homeostasis

Yanxia Wei, Jing Gao, Yanbo Kou, +8

The FASEB Journal

InflammationChronic Inflammatory DiseasesDysbiosisMucosal ImmunologyMedicine +13

TWIST1+FAP+ fibroblasts in the pathogenesis of intestinal fibrosis in Crohn’s disease

Yao Zhang, Jiaxin Wang, Hongxiang Sun, +13

Journal of Clinical Investigation

Metabolic regulation of T cell development by Sin1–mTORC2 is mediated by pyruvate kinase M2

Xinxing Ouyang, Yuheng Han, Guojun Qu, +10

Journal of Molecular Cell Biology

Novel Mtorc2-ppar-γ-pkm2 PathwayMolecular RegulationMetabolic RemodelingCellular PhysiologySignaling Pathway +21

Commensal Bacteria Impact a Protozoan’s Integration into the Murine Gut Microbiota in a Dietary Nutrient-Dependent Manner

Yanxia Wei, Jing Gao, Yanbo Kou, +6

Applied and Environmental Microbiology

Intestinal Epithelial Cell–Derived LKB1 Suppresses Colitogenic Microbiota

Xianan Liu, Jinfeng Lü, Zhenshan Liu, +12

The Journal of Immunology

The Probiotic Effectiveness in Preventing Experimental Colitis Is Correlated With Host Gut Microbiota

Sharmila Suwal, Qiong Wu, Wenli Liu, +10

Frontiers in Microbiology