Concepedia

ID-CRISPR: A CRISPR/Cas12a platform for label-free and sensitive detection of rare mutant alleles using self-interference DNA hydrogel reporter

Anni Deng, Zeyin Mao, Xiangyu Jin, Wenqi Lv, Leyang Huang, Rongxin Fu, Guoliang Huang

Biosensors and Bioelectronics · 2025 · 15 citations · 38 references

DOI

Concepts

References

38

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen, Enbo Ma, Lucas B. Harrington et al. · Science · 2018 · 4.4K citations

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CRISPR–Cas12-based detection of SARS-CoV-2

James P. Broughton, Xianding Deng, Guixia Yu et al. · Nature Biotechnology · 2020 · 2.8K citations · Full text

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Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

Jonathan S. Gootenberg, Omar O. Abudayyeh, Max J. Kellner et al. · Science · 2018 · 2.6K citations · Full text

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CRISPR-Cas12a-assisted nucleic acid detection

Shiyuan Li, Qiuxiang Cheng, Jing-Man Wang et al. · Cell Discovery · 2018 · 1.5K citations · Full text

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Exploring the Trans‐Cleavage Activity of CRISPR‐Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

Yifan Dai, Rodrigo A. Somoza, Liu Wang et al. · Angewandte Chemie International Edition · 2019 · 645 citations · Full text

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