Dynamic regulation combined with systematic metabolic engineering for high-level palmitoleic acid accumulation in oleaginous yeast

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +12

Gene Ontology: tool for the unification of biology

Michael Ashburner, Catherine A. Ball, Judith A. Blake et al. · Nature Genetics · 2000 · 44.6K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +9

fastp: an ultra-fast all-in-one FASTQ preprocessor

Shifu Chen, Yanqing Zhou, Yaru Chen et al. · Bioinformatics · 2018 · 29.7K citations · Full text

Computing, Computer Engineering, Computer Science +8

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

Bo Li, Colin N. Dewey · BMC Bioinformatics · 2011 · 23.4K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +15

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

Mihaela Pertea, Geo Pertea, Corina Antonescu et al. · Nature Biotechnology · 2015 · 15.5K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +10