Concepedia

Exogenous hydrogen sulfide and NOX2 inhibition mitigate ferroptosis in pressure-induced retinal ganglion cell damage

Yuan Feng, Xiaosha Wang, Panpan Li, Xin Shi, Verena Prokosch, Hanhan Liu

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2025 · 17 citations · 40 references

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Abstract

S donors are positioning as a promising multi-target therapy for glaucoma, with NOX2 emerging as a key regulator of ferroptosis.

References

40

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest

Damian Szklarczyk, Rebecca Kirsch, Mikaela Koutrouli et al. · Nucleic Acids Research · 2022 · 8.8K citations · Full text

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Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch et al. · Cell · 2014 · 7.5K citations · Full text

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Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

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H <sub>2</sub> S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase

Guangdong Yang, Lingyun Wu, Bo Jiang et al. · Science · 2008 · 2.3K citations · Full text

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