Concepedia

Nepetin limits NLRP3 inflammasome activation and alleviates NLRP3-driven inflammatory diseases via PINK1-dependent mitophagy

Wenjie Bu, Sisi Li, Chang Liu, Yuehua Wang, Jianrong Lu, D. G. Zheng, Zhe-yu Fan, Yi Yu, Wei Zhang, Yunlong Bai

Free Radical Biology and Medicine · 2024 · 20 citations · 22 references

DOI

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References

22

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi, Yue Zhao, Kun Wang et al. · Nature · 2015 · 6.5K citations

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A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada, Timothy R. Crother, Justin N. Karlin et al. · Immunity · 2012 · 2.2K citations · Full text

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PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

Lesley A. Kane, Michael Lazarou, Adam I. Fogel et al. · The Journal of Cell Biology · 2014 · 1.3K citations · Full text

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New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Zhenyu Zhong, Shuang Liang, Elsa Sánchez‐López et al. · Nature · 2018 · 1.2K citations

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