Sishen Pill & Tongxieyaofang ameliorated ulcerative colitis through the activation of HIF-1α acetylation by gut microbiota-derived propionate and butyrate

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

Wenjing Yang, Tianming Yu, Xiangsheng Huang et al. · Nature Communications · 2020 · 1K citations · Full text

Life Sciences, Immunology, Nutritional Sciences +17

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice

Giada De Palma, Michael D. J. Lynch, Jun Lü et al. · Science Translational Medicine · 2017 · 506 citations

Life Sciences, Immunology, Microbiology +16

Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway

Hui Yan, Kolapo M. Ajuwon · PLoS ONE · 2017 · 430 citations · Full text

Life Sciences, Cell Biology, Physiology +17

Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation

Jesús Cosín‐Roger, Simona Simmen, Hassan Melhem et al. · Nature Communications · 2017 · 314 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Gut microbiota-derived inosine from dietary barley leaf supplementation attenuates colitis through PPARγ signaling activation

Daotong Li, Yu Feng, Meiling Tian et al. · Microbiome · 2021 · 265 citations · Full text

Life Sciences, Immunology, Microbiology +17