“Resource-Conserving” engineered nanoparticles Mediate disulfidptosis by overcoming resistance to ferroptosis for antitumor immunotherapy

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis

Xiaoguang Liu, Litong Nie, Yilei Zhang et al. · Nature Cell Biology · 2023 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11

Xueting Lang, Michael D. Green, Weimin Wang et al. · Cancer Discovery · 2019 · 1.1K citations · Full text

Medicine, Immunology, Oncology +12

Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer

Xiaoguang Liu, Kellen Olszewski, Yilei Zhang et al. · Nature Cell Biology · 2020 · 595 citations · Full text

Life Sciences, Biochemistry, Cancer Biology +17

An Adenosine Triphosphate-Responsive Autocatalytic Fenton Nanoparticle for Tumor Ablation with Self-Supplied H₂O₂ and Acceleration of Fe(III)/Fe(II) Conversion

Lu Zhang, Shuangshuang Wan, Chu‐Xin Li et al. · Nano Letters · 2018 · 586 citations

Natural Sciences, Chemical Engineering, Oncology +17