α-Synuclein disrupts microglial autophagy through STAT1-dependent suppression of Ulk1 transcription

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 6.8K citations · Full text

Mtor Regulate Autophagy, Mitophagy, Cell Autophagy +10

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

E. Ray Dorsey, Alexis Elbaz, Emma Nichols et al. · The Lancet Neurology · 2018 · 2.6K citations · Full text

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

Paula Desplats, He-Jin Lee, Eun-Jin Bae et al. · Proceedings of the National Academy of Sciences · 2009 · 1.4K citations · Full text

Synaptic Transmission, Neuronal Cell Death, Immunology +25

Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates

Laura A. Volpicelli‐Daley, Kelvin C. Luk, Virginia M.‐Y. Lee · Nature Protocols · 2014 · 735 citations · Full text

Exogenous α-Synuclein, Neurodegenerative Diseases, Neurobiology Of Disease +9

<scp>ULK</scp> 1 translocates to mitochondria and phosphorylates <scp>FUNDC</scp> 1 to regulate mitophagy

Wenxian Wu, Weili Tian, Zhe Hu et al. · EMBO Reports · 2014 · 555 citations · Full text

Mitophagy, Signal Transduction, Biochemistry +11