Concepedia

Targeting NQO1 induces ferroptosis and triggers anti-tumor immunity in immunotherapy-resistant KEAP1-deficient cancers

Zhennan Yuan, Boyu Qin, Rulong Hu, Rui Miao, Yang Zhou, Lei Wang, Tong Liu

Drug Resistance Updates · 2024 · 30 citations · 30 references

DOI

Concepts

References

30

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Freddie Bray, Mathieu Laversanne, Hyuna Sung et al. · CA A Cancer Journal for Clinicians · 2024 · 23.1K citations · Full text

, , +16

Ferroptosis as a p53-mediated activity during tumour suppression

Le Jiang, Ning Kon, Tongyuan Li et al. · Nature · 2015 · 3.4K citations · Full text

, , +14

Role of Mitochondria in Ferroptosis

Minghui Gao, Jun-Mei Yi, Jiajun Zhu et al. · Molecular Cell · 2018 · 2.1K citations · Full text

, , +10

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer

Chao Mao, Xiaoguang Liu, Yilei Zhang et al. · Nature · 2021 · 1.8K citations · Full text

, , +14

A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers

Pranavi Koppula, Guang Lei, Yilei Zhang et al. · Nature Communications · 2022 · 459 citations · Full text

, , +17