Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

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Inflammation, Signal Transduction, Signaling Pathway +12

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

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Inflammation, Anti-inflammatory, Signal Transduction +8

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

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Inflammation, Apoptosis, Cell Death +7

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

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Medicine, Apoptosis, Pyroptosis +9

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

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