Lisa D. J. Schiffelers

Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

Paul-Albert Koenig, Hrishikesh Das, Hejun Liu et al. · Science · 2021 · 436 citations · Full text

Nanoparticles, Nanomedicine, Virus Structure +15

Brain endothelial GSDMD activation mediates inflammatory BBB breakdown

Chao Wei, Wei Jiang, Ruiyu Wang et al. · Nature · 2024 · 189 citations

Inflammation, Blood–brain Barrier, Medicine +11

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection

Lea‐Marie Jenster, Karl-Elmar Lange, Sabine Normann et al. · The Journal of Experimental Medicine · 2022 · 100 citations · Full text

Inflammation, Inflammatory Responses, Signal Transduction +15

Nanobodies dismantle post‐pyroptotic ASC specks and counteract inflammation <i>in vivo</i>

Damien Bertheloot, Carlos W. Wanderley, Ayda Henriques Schneider et al. · EMBO Molecular Medicine · 2022 · 43 citations · Full text

Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells

Iztok Urbančič, Lisa D. J. Schiffelers, Edward Jenkins et al. · FEBS Letters · 2021 · 37 citations · Full text