Intelligent Pharmacy · 2024 · 100 citations · 13 references
MedicineBiomedical InformaticsHealth InformaticsPharmacogeneticsPharmacogenomicsPrecision MedicineClinical Implementation Of PharmacogeneticsClinical Implementation Of PharmacogenomicsDrug Repurposing InformaticsPharmaceutical Data IntegrationPharmacogenomic Data InterpretationPopulation PharmacogenomicsIndividualized Drug TherapyIntegration Of Pharmacogenomic Results Into Care PlansPersonalized Medicine ImplementationPharmacogenomics Data IntegrationTranslational Pharmacogenetics
This paper examines the transformative impact of artificial intelligence (AI) on pharmacogenomics, signaling a paradigm shift in personalized medicine. With a focus on enhancing drug response prediction and treatment optimization, AI, particularly machine learning and deep learning algorithms, navigates the complexity of genomic data. By elucidating intricate relationships between genetic factors and drug responses, AI augments the identification of genetic markers and contributes to the development of comprehensive models. The review emphasizes AI's role in guiding treatment decisions, minimizing adverse reactions, and optimizing drug dosages in clinical settings. Ethical considerations, challenges, and future directions are also discussed. This work underscores the synergy of AI and pharmacogenomics, offering a more effective and patient-centric approach to drug therapy, marking a significant advancement in the field of personalized medicine.
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Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
Brent M. Kuenzi, Jisoo Park, Samson Fong et al. · Cancer Cell · 2020 · 525 citations · Full text
Medicine, Oncology, Pharmacology +17
Pharmacogenomics: The Right Drug to the Right Person
T P Aneesh · Journal of Clinical Medicine Research · 2009 · 114 citations · Full text