Concepedia

The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Yijian Qiu, Olivia T. Stamatatos, Qingting Hu, Jed Ruiter Swain, Suzanne Russo, Ava Sann, Ana S.H. Costa, Sara Violante, David L. Spector, Justin R. Cross,

Nature Metabolism · 2024 · 25 citations · 49 references

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49

The Determination of Enzyme Dissociation Constants

Hans Lineweaver, Dean Burk · Journal of the American Chemical Society · 1934 · 12.1K citations

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Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

Ting‐Chao Chou · Cancer Research · 2010 · 5.7K citations

, , +15

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Richard Possemato, Kevin M. Marks, Yoav D. Shaul et al. · Nature · 2011 · 1.7K citations · Full text

, , +16

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

, , +13

Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

Matt I. Gross, Susan D. Demo, Jennifer B. Dennison et al. · Molecular Cancer Therapeutics · 2014 · 1.1K citations

, , +16