Concepedia

GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway

Xiayun Li, He Sun, Liyun Zhang, Hongliang Liang, Bin Zhang, Jiachang Yang, Xiangyan Peng, Jingwei Sun, Yang Zhou, Mengen Zhai,

European Journal of Pharmacology · 2024 · 31 citations · 45 references

DOI

Concepts

References

45

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

Theresa A. McDonagh, Marco Metra, Marianna Adamo et al. · European Heart Journal · 2021 · 13K citations · Full text

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Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury

Ning Li, Wei Wang, Heng Zhou et al. · Free Radical Biology and Medicine · 2020 · 652 citations · Full text

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The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

Paul J. Emmerson, Feng Wang, Yong Du et al. · Nature Medicine · 2017 · 650 citations

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GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance

Harding H. Luan, Andrew Wang, Brandon K. Hilliard et al. · Cell · 2019 · 509 citations · Full text

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Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer

Shumin Ouyang, Huaxuan Li, Linlin Lou et al. · Redox Biology · 2022 · 489 citations · Full text

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