Paul J. Emmerson

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

Paul J. Emmerson, Feng Wang, Yong Du et al. · Nature Medicine · 2017 · 626 citations

Metabolic Syndrome, Energy Metabolism, Biochemistry +12

Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Francis S. Willard, Jonathan D. Douros, M Gabe et al. · JCI Insight · 2020 · 439 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Insulin Signaling +20

Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes.

Paul J. Emmerson, M R Liu, J H Woods et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 230 citations

Characterization of opioid agonist efficacy in a C6 glioma cell line expressing the mu opioid receptor.

Paul J. Emmerson, Mary J. Clark, Alfred Mansour et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 180 citations

Structural determinants of dual incretin receptor agonism by tirzepatide

Bingfa Sun, Francis S. Willard, Dan Feng et al. · Proceedings of the National Academy of Sciences · 2022 · 105 citations · Full text

Glycobiology, Pharmacotherapy, Insulin Signaling +20