Concepedia

Lactylation: Linking the Warburg effect to DNA damage repair

Peng Sun, Leina Ma, Zhimin Lu

Cell Metabolism · 2024 · 39 citations · 7 references

DOI

Concepts

References

7

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji et al. · Nature · 2011 · 1K citations · Full text

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ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

Weiwei Yang, Yanhua Zheng, Yan Xia et al. · Nature Cell Biology · 2012 · 915 citations · Full text

, , +16

PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Weiwei Yang, Yan Xia, David H. Hawke et al. · Cell · 2012 · 847 citations · Full text

, , +12

Histone lactylation: epigenetic mark of glycolytic switch

Xiaofeng Dai, Xinyu Lv, Erik W. Thompson et al. · Trends in Genetics · 2021 · 195 citations

, , +14

Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma

Guanzhang Li, Di Wang, You Zhai et al. · Cell Metabolism · 2024 · 186 citations · Full text

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