Concepedia

Design, synthesis, and anti-mycobacterial evaluation of 1,8-naphthyridine-3-carbonitrile analogues

Yogesh Mahadu Khetmalis, S. V. Shobha, Adinarayana Nandikolla, Ala Chandu, Sankaranarayanan Murugesan, Muthyala Murali Krishna Kumar, Kondapalli Venkata Gowri Chandra Sekhar

RSC Advances · 2024 · 10 citations · 30 references

DOIFull text

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Concepts

Abstract

predictions were utilized to assess the ADMET properties of the final compounds. A suitable single crystal was developed and analyzed for compound ANA-5 to gain a deeper understanding of the compounds' structures.

References

30

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Antoine Daina, Olivier Michielin, Vincent Zoete · Scientific Reports · 2017 · 17.1K citations · Full text

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Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines

Ajit K Parhi, Yong‐Zheng Zhang, Kurt W. Saionz et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 166 citations · Full text

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The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Edward P. Garvey, Brian A. Johns, Margaret Gartland et al. · Antimicrobial Agents and Chemotherapy · 2007 · 76 citations · Full text

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Tuberculosis: An Overview of the Immunogenic Response, Disease Progression, and Medicinal Chemistry Efforts in the Last Decade toward the Development of Potential Drugs for Extensively Drug-Resistant Tuberculosis Strains

Akanksha Sharma, Maria De Rosa, Neha Singla et al. · Journal of Medicinal Chemistry · 2021 · 59 citations

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1,8-Naphthyridine-3-carboxamide derivatives with anticancer and anti-inflammatory activity

Vivek Kumar, Manu Jaggi, Anu Singh et al. · European Journal of Medicinal Chemistry · 2009 · 46 citations

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