Concepedia

Topical application of a P2X2/P2X3 purine receptor inhibitor suppresses the bitter taste of medicines and other taste qualities

Linda J. Flammer, Hillary Ellis, Natasha Rivers, Lauren Caronia, Misgana Y. Ghidewon, Carol M. Christensen, Peihua Jiang, Paul Breslin, Michael G. Tordoff

British Journal of Pharmacology · 2024 · 12 citations · 35 references

DOIFull text

Open access

Abstract

This is the first time a universal, reversible taste blocker in humans has been reported. Topical application of P2X2/P2X3 inhibitor to suppress bitterness may improve medical compliance.

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