Integrating spatial and single-cell transcriptomics reveals tumor heterogeneity and intercellular networks in colorectal cancer

Comprehensive Integration of Single-Cell Data

Tim Stuart, Andrew Butler, Paul Hoffman et al. · Cell · 2019 · 16K citations · Full text

Engineering, Biomedical Data Integration, Data Science +11

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.1K citations · Full text

Engineering, Genetics, Multiomics +17

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

Cole Trapnell, Davide Cacchiarelli, Jonna Grimsby et al. · Nature Biotechnology · 2014 · 7.4K citations · Full text

Pattern Formation, Developmental Biology, Cell Division +12

SCENIC: single-cell regulatory network inference and clustering

Sara Aibar, Carmen Bravo González‐Blas, Thomas Moerman et al. · Nature Methods · 2017 · 6.5K citations · Full text

Functional Genomics, Engineering, Medicine +9

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

Dvir Aran, Agnieszka Looney, Leqian Liu et al. · Nature Immunology · 2019 · 5K citations

Lung Single-cell Sequencing, Reference-based Analysis, Transitional Profibrotic Macrophage +12