Concepedia

Spatial Transcriptomic Integration

Spatial Transcriptomic Integration is a computational framework that combines single-cell RNA sequencing data with spatially resolved transcriptomic data to reconstruct gene expression patterns within the architectural context of tissues, thereby preserving both cellular resolution and spatial localization.

48

Publications

4.7K

Citations

384

Authors

135

Institutions

Publications per year

2017–2026

47

Parents

Publications

48

Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas

Reuben Moncada, Dalia Barkley, Florian Wagner et al. · Nature Biotechnology · 2020 · 1.1K citations

, , +16

SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes

Marc Elosua-Bayés, Paula Nieto, Elisabetta Mereu et al. · Nucleic Acids Research · 2021 · 755 citations · Full text

, , +16

Benchmarking spatial and single-cell transcriptomics integration methods for transcript distribution prediction and cell type deconvolution

Bin Li, Wen Zhang, Chuang Guo et al. · Nature Methods · 2022 · 469 citations

, , +16

Alignment and integration of spatial transcriptomics data

Ron Zeira, Max Land, Alexander Strzalkowski et al. · Nature Methods · 2022 · 306 citations · Full text

, , +13

Delineating the dynamic evolution from preneoplasia to invasive lung adenocarcinoma by integrating single-cell RNA sequencing and spatial transcriptomics

Jianfei Zhu, Yue Fan, Yanlu Xiong et al. · Experimental & Molecular Medicine · 2022 · 195 citations · Full text

, , +17

1–5 of 48

Authors

384

  1. RZ
    Ron Zeira

    Princeton University, United States

    3 publications · 345 citations

    3

    h-index

  2. SG
    Shila Ghazanfar

    The University of Sydney, Australia

    3 publications · 124 citations

    3

    h-index

  3. SZ
    Shihua Zhang

    Academy of Mathematics and Systems Science, China

    3 publications · 167 citations

    3

    h-index

  4. BJ
    Benjamin J. Raphael

    Princeton University, United States

    3 publications · 345 citations

    3

    h-index

  5. KD
    Kangning Dong

    Academy of Mathematics and Systems Science, China

    3 publications · 167 citations

    3

    h-index

1–5 of 384

Institutions

135

  1. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    12 publications

    1.1K citations

  2. Wellcome Sanger Institute

    Cambridge, United Kingdom

    4 h-index

    27 publications

    1.7K citations

  3. University of Chinese Academy of Sciences

    Beijing, China

    4 h-index

    6 publications

    227 citations

  4. Academy of Mathematics and Systems Science

    Beijing, China

    3 h-index

    8 publications

    487 citations

  5. Princeton University

    Princeton, United States

    3 h-index

    9 publications

    1.3K citations

  6. Agency for Science, Technology and Research

    Singapore, Singapore

    3 h-index

    5 publications

    329 citations

  7. East China Normal University

    Shanghai, China

    3 h-index

    3 publications

    196 citations

  8. European Bioinformatics Institute

    Cambridge, United Kingdom

    3 h-index

    7 publications

    502 citations

1–8 of 135

Venues

  1. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 12 publications · 348 citations

    13

    h-index

  2. Nature Communications

    2 publications · 142 citations

    3

    h-index

  3. Nature Biotechnology

    2 publications · 1.2K citations

    2

    h-index

  4. Genome biology

    2 publications · 167 citations

    2

    h-index

  5. arXiv (Cornell University)

    Repository · 2 publications · 122 citations

    2

    h-index

1–5