TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

Charleen T. Chu, Jing Ji, Ruben K. Dagda et al. · Nature Cell Biology · 2013 · 1K citations · Full text

Mitophagy, Mitochondrial Function, Biochemistry +10

Hepatocytes direct the formation of a pro-metastatic niche in the liver

Jae W. Lee, Meredith L. Stone, Paige M. Porrett et al. · Nature · 2019 · 407 citations · Full text

Hepatology, Liver Physiology, Pro-metastatic Niche +10

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

Ji-An Pan, Yu Sun, Ya-Ping Jiang et al. · Molecular Cell · 2016 · 253 citations · Full text

Redox Signaling, Redox Regulator, Genetics +8

STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib

Yahui Zheng, Chong Huang, Lu Lu et al. · Journal of Hematology & Oncology · 2021 · 155 citations · Full text

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

Kai Hou, Jianliang Shen, Junrong Yan et al. · EBioMedicine · 2021 · 134 citations · Full text