Regulation of FSP1 myristoylation by NADPH: A novel mechanism for ferroptosis inhibition

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 17K citations · Full text

Iron Deficiency, Nonapoptotic Cell Death, Metalloprotein +9

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker, Joseph M. Hendricks, Zhipeng Li et al. · Nature · 2019 · 3.4K citations · Full text

Aldo-keto Reductase, Biochemistry, Natural Sciences +10

FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll, Florêncio Porto Freitas, Ron Shah et al. · Nature · 2019 · 3K citations · Full text

Redox Signaling, Signal Transduction, Biochemistry +7

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Wan Seok Yang, Katherine J. Kim, Michael M. Gaschler et al. · Proceedings of the National Academy of Sciences · 2016 · 2.2K citations · Full text

Energy-stress-mediated AMPK activation inhibits ferroptosis

Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang et al. · Nature Cell Biology · 2020 · 1.1K citations · Full text

Reductive Stress, Signal Transduction, Biochemistry +7